Phenotypes associated with this allele

• Allele Symbol: Tg(ACTA1-Ctss)1Jmol
• Allele Name: transgene insertion 1, Jeffery Molkentin
• Allele ID: MGI:5765989
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(ACTA1-Ctss)1Jmol/?	FVB/N-Tg(ACTA1-Ctss)1Jmol	MGI:5779562

Genotype
MGI:5779562

tg1

• Allelic Composition: Tg(ACTA1-Ctss)1Jmol/?
• Genetic Background: FVB/N-Tg(ACTA1-Ctss)1Jmol

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired exercise endurance ( J:230788 )

• treadmill running time is decreased at 2 and 5 months

homeostasis/metabolism

impaired exercise endurance ( J:230788 )

• treadmill running time is decreased at 2 and 5 months

muscle

centrally nucleated skeletal muscle fibers ( J:230788 )

• accumulation of centrally localized nuclei in skeletal muscle myofibers at 2 months of age

skeletal muscle fibrosis ( J:230788 )

dystrophic muscle ( J:230788 )

• muscle tissue is replaced by fibrosis and fatty tissue

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Duchenne muscular dystrophy		DOID:11723	OMIM:310200	J:230788