Phenotypes associated with this allele

• Allele Symbol: Arhgef6^{tm2e.1(EUCOMM)Wtsi}
• Allele Name: targeted mutation 2e.1, Wellcome Trust Sanger Institute
• Allele ID: MGI:5766158
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arhgef6^tm2e.1(EUCOMM)Wtsi/Arhgef6^tm2e.1(EUCOMM)Wtsi	C57BL/6N-Arhgef6^tm2e.1(EUCOMM)Wtsi/Tcp	MGI:5797374
ot2	Arhgef6^tm2e.1(EUCOMM)Wtsi/Y	C57BL/6N-Arhgef6^tm2e.1(EUCOMM)Wtsi/Tcp	MGI:5797373

Genotype
MGI:5797374

hm1

• Allelic Composition: Arhgef6^{tm2e.1(EUCOMM)Wtsi}/Arhgef6^{tm2e.1(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Arhgef6^{tm2e.1(EUCOMM)Wtsi}/Tcp
• Cell Lines: EPD0828_1_D12

Data Sources

IMPC Data for Arhgef6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - TCP

homeostasis/metabolism

increased circulating potassium level ( J:211773 )

♀

IMPC - TCP

increased circulating aspartate transaminase level ( J:211773 )

♀

IMPC - TCP

immune system

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - TCP

Genotype
MGI:5797373

ot2

• Allelic Composition: Arhgef6^{tm2e.1(EUCOMM)Wtsi}/Y
• Genetic Background: C57BL/6N-Arhgef6^{tm2e.1(EUCOMM)Wtsi}/Tcp
• Cell Lines: EPD0828_1_D12

Data Sources

IMPC Data for Arhgef6

immune system

enlarged lymph nodes ( J:211773 )

♂

IMPC - TCP