Phenotypes associated with this allele

• Allele Symbol: Cdk4^{tm1b(NCOM)Mfgc}
• Allele Name: targeted mutation 1b, Mammalian Functional Genomics Centre
• Allele ID: MGI:5766181
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cdk4^tm1b(NCOM)Mfgc/Cdk4^tm1b(NCOM)Mfgc	C57BL/6N-Cdk4^tm1b(NCOM)Mfgc/Tcp	MGI:5797428
ht2	Cdk4^tm1b(NCOM)Mfgc/Cdk4^+	C57BL/6N-Cdk4^tm1b(NCOM)Mfgc/Tcp	MGI:5797427

Genotype
MGI:5797428

hm1

• Allelic Composition: Cdk4^{tm1b(NCOM)Mfgc}/Cdk4^{tm1b(NCOM)Mfgc}
• Genetic Background: C57BL/6N-Cdk4^{tm1b(NCOM)Mfgc}/Tcp
• Cell Lines: M00049_C_390W_F08

Data Sources

IMPC Data for Cdk4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo size ( J:211773 )

♂

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

♂

IMPC - TCP

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

reproductive system

female infertility ( J:211773 )

♀

IMPC - TCP

male infertility ( J:211773 )

♂

IMPC - TCP

vision/eye

microphthalmia ( J:211773 )

♂

IMPC - TCP

Genotype
MGI:5797427

ht2

• Allelic Composition: Cdk4^{tm1b(NCOM)Mfgc}/Cdk4⁺
• Genetic Background: C57BL/6N-Cdk4^{tm1b(NCOM)Mfgc}/Tcp
• Cell Lines: M00049_C_390W_F08

Data Sources

IMPC Data for Cdk4

craniofacial

abnormal cranium morphology ( J:211773 )

IMPC - TCP

growth/size/body

decreased body length ( J:211773 )

♀

IMPC - TCP

hematopoietic system

increased mean corpuscular volume ( J:211773 )

♂

IMPC - TCP

skeleton

abnormal cranium morphology ( J:211773 )

IMPC - TCP