Phenotypes associated with this allele

• Allele Symbol: Egr1^{tm1b(NCOM)Mfgc}
• Allele Name: targeted mutation 1b, Mammalian Functional Genomics Centre
• Allele ID: MGI:5766183
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Egr1^tm1b(NCOM)Mfgc/Egr1^tm1b(NCOM)Mfgc	C57BL/6N-Egr1^tm1b(NCOM)Mfgc/Tcp	MGI:5797501
ht2	Egr1^tm1b(NCOM)Mfgc/Egr1^+	C57BL/6N-Egr1^tm1b(NCOM)Mfgc/Tcp	MGI:5797500

Genotype
MGI:5797501

hm1

• Allelic Composition: Egr1^{tm1b(NCOM)Mfgc}/Egr1^{tm1b(NCOM)Mfgc}
• Genetic Background: C57BL/6N-Egr1^{tm1b(NCOM)Mfgc}/Tcp
• Cell Lines: M00043_C_384W_A04

Data Sources

IMPC Data for Egr1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

abnormal neural tube closure ( J:211773 )

IMPC - TCP

endocrine/exocrine glands

absent seminal vesicle ( J:211773 )

♂

IMPC - TCP

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

nervous system

abnormal neural tube closure ( J:211773 )

IMPC - TCP

abnormal forebrain development ( J:211773 )

IMPC - TCP

abnormal hindbrain development ( J:211773 )

IMPC - TCP

abnormal midbrain development ( J:211773 )

IMPC - TCP

abnormal optic disk morphology ( J:211773 )

♀

IMPC - TCP

reproductive system

absent seminal vesicle ( J:211773 )

♂

IMPC - TCP

small uterus ( J:211773 )

♀

IMPC - TCP

female infertility ( J:211773 )

♀

IMPC - TCP

male infertility ( J:211773 )

♂

IMPC - TCP

vision/eye

abnormal optic disk morphology ( J:211773 )

♀

IMPC - TCP

Genotype
MGI:5797500

ht2

• Allelic Composition: Egr1^{tm1b(NCOM)Mfgc}/Egr1⁺
• Genetic Background: C57BL/6N-Egr1^{tm1b(NCOM)Mfgc}/Tcp
• Cell Lines: M00043_C_384W_A04

Data Sources

IMPC Data for Egr1

growth/size/body

decreased body length ( J:211773 )

♀

IMPC - TCP

hematopoietic system

increased lymphocyte cell number ( J:211773 )

♀

IMPC - TCP

immune system

increased lymphocyte cell number ( J:211773 )

♀

IMPC - TCP

limbs/digits/tail

short tibia ( J:211773 )

IMPC - TCP

skeleton

short tibia ( J:211773 )

IMPC - TCP