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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sdcbptm1c(KOMP)Wtsi
targeted mutation 1c, Wellcome Trust Sanger Institute
MGI:5766222
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Sdcbptm1c(KOMP)Wtsi/Sdcbp+
Tsc2tm1Tno/Tsc2+
Tg(Camk2a-cre)2Gsc/0 		involves: 129S4/SvJae * C57BL/6N * FVB/N MGI:5766247


Genotype
MGI:5766247
cn1
Allelic
Composition		 Sdcbptm1c(KOMP)Wtsi/Sdcbp+
Tsc2tm1Tno/Tsc2+
Tg(Camk2a-cre)2Gsc/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6N * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sdcbptm1c(KOMP)Wtsi mutation (0 available); any Sdcbp mutation (27 available)
Tg(Camk2a-cre)2Gsc mutation (2 available)
Tsc2tm1Tno mutation (0 available); any Tsc2 mutation (78 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:222712 )
N
• mice exhibit normal electrophysiological properties
abnormal dendrite morphology ( J:222712 )
• dendritic protrusions exhibit increased width and density and reduced length compared to in Tsc2tm1Tno heterozygotes
• however, mice exhibit normal spine and shaft synapse density




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory