Phenotypes associated with this allele

• Allele Symbol: Stat1^{tm2b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 2b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5766744
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stat1^tm2b(EUCOMM)Wtsi/Stat1^tm2b(EUCOMM)Wtsi	C57BL/6N-Stat1^tm2b(EUCOMM)Wtsi/Orl	MGI:5797849

Genotype
MGI:5797849

hm1

• Allelic Composition: Stat1^{tm2b(EUCOMM)Wtsi}/Stat1^{tm2b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Stat1^{tm2b(EUCOMM)Wtsi}/Orl
• Cell Lines: EPD0607_3_A10

Data Sources

IMPC Data for Stat1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired righting response ( J:211773 )

♂

IMPC - ICS

abnormal gait ( J:211773 )

♂

IMPC - ICS

hematopoietic system

decreased mean corpuscular hemoglobin ( J:211773 )

IMPC - ICS

decreased mean corpuscular volume ( J:211773 )

IMPC - ICS

decreased lymphocyte cell number ( J:211773 )

IMPC - ICS

increased leukocyte cell number ( J:211773 )

IMPC - ICS

increased basophil cell number ( J:211773 )

IMPC - ICS

increased eosinophil cell number ( J:211773 )

♀

IMPC - ICS

increased neutrophil cell number ( J:211773 )

IMPC - ICS

increased lymphocyte cell number ( J:211773 )

IMPC - ICS

increased large unstained cell number ( J:211773 )

♀

IMPC - ICS

increased monocyte cell number ( J:211773 )

IMPC - ICS

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - ICS

immune system

decreased lymphocyte cell number ( J:211773 )

IMPC - ICS

increased leukocyte cell number ( J:211773 )

IMPC - ICS

increased basophil cell number ( J:211773 )

IMPC - ICS

increased eosinophil cell number ( J:211773 )

♀

IMPC - ICS

increased neutrophil cell number ( J:211773 )

IMPC - ICS

increased lymphocyte cell number ( J:211773 )

IMPC - ICS

increased large unstained cell number ( J:211773 )

♀

IMPC - ICS

increased monocyte cell number ( J:211773 )

IMPC - ICS

enlarged lymph nodes ( J:211773 )

IMPC - ICS

skeleton

decreased bone mineral content ( J:211773 )

IMPC - ICS