Phenotypes associated with this allele

• Allele Symbol: Ffar2^tm1Soff
• Allele Name: targeted mutation 1, Stefan Offermanns
• Allele ID: MGI:5770445
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ffar2^tm1Soff/Ffar2^tm1Soff	B6.129-Ffar2^tm1Soff	MGI:5770564

Genotype
MGI:5770564

hm1

• Allelic Composition: Ffar2^tm1Soff/Ffar2^tm1Soff
• Genetic Background: B6.129-Ffar2^tm1Soff

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:227939 )

N • when fed normal chow or a high-fat diet, mice exhibit normal basal metabolic rate and energy expenditure

increased circulating insulin level ( J:227939 )

• however, mice fed a normal diet exhibit normal insulin levels

• slightly in mice fed a high-fat diet after a glucose challenge

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:227939 )

N • islets exhibit normal acetate-induced, PTX-sensitive inhibition of glucose stimulated insulin secretion