Phenotypes associated with this allele

• Allele Symbol: Cdh23^{tm2b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 2b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5775000
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cdh23^tm2b(EUCOMM)Wtsi/Cdh23^tm2b(EUCOMM)Wtsi	C57BL/6N-Cdh23^tm2b(EUCOMM)Wtsi/Wtsi	MGI:6262087

Genotype
MGI:6262087

hm1

• Allelic Composition: Cdh23^{tm2b(EUCOMM)Wtsi}/Cdh23^{tm2b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Cdh23^{tm2b(EUCOMM)Wtsi}/Wtsi
• Cell Lines: MEPD1008_2_A03

Data Sources

IMPC Data for Cdh23

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - WTSI

behavior/neurological

absent pinna reflex ( J:211773 )

IMPC - WTSI

impaired righting response ( J:211773 )

IMPC - WTSI

trunk curl ( J:211773 )

IMPC - WTSI

abnormal gait ( J:211773 )

IMPC - WTSI

stereotypic behavior ( J:211773 )

IMPC - WTSI

growth/size/body

increased lean body mass ( J:211773 )

♂

IMPC - WTSI

decreased body length ( J:211773 )

♀

IMPC - WTSI

hematopoietic system

increased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - WTSI

decreased leukocyte cell number ( J:211773 )

♂

IMPC - WTSI

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - WTSI

decreased fasting circulating glucose level ( J:211773 )

♂

IMPC - WTSI

decreased circulating calcium level ( J:211773 )

IMPC - WTSI

increased circulating sodium level ( J:211773 )

IMPC - WTSI

increased circulating chloride level ( J:211773 )

IMPC - WTSI

immune system

decreased leukocyte cell number ( J:211773 )

♂

IMPC - WTSI

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - WTSI

skeleton

increased bone mineral content ( J:211773 )

♂

IMPC - WTSI