Phenotypes associated with this allele

• Allele Symbol: Tg(Myh6-Strit1)#Eno
• Allele Name: transgene insertion, Eric N Olson
• Allele ID: MGI:5776137
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Myh6-Strit1)#Eno/0	involves: C57BL/6	MGI:5776161

Genotype
MGI:5776161

tg1

• Allelic Composition: Tg(Myh6-Strit1)#Eno/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal myocardial fiber physiology ( J:229305 )

• peak calcium transient amplitude and sarcoplasmic reticulum calcium load is increased compared to in wild-type myocytes

• pacing-introduced calcium transient decay rates is enhanced compared to in wild-type myocytes

• higher baseline measurements of contractility

• reduced beta-adrenergic stimulation response by isoproterenol

• however, the decay rate of caffeine-induced calcium transients is normal