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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mapttm1.1(FUS)Neas
targeted mutation 1.1, Neil A Shneider
MGI:5776229
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mapttm1.1(FUS)Neas/Mapttm1.1(FUS)Neas B6J.129P2(129S)-Mapttm1.1(FUS)Neas MGI:5823843
ht2
 		Mapttm1.1(FUS)Neas/Mapt+ B6J.129P2(129S)-Mapttm1.1(FUS)Neas MGI:5823842


Genotype
MGI:5823843
hm1
Allelic
Composition		 Mapttm1.1(FUS)Neas/Mapttm1.1(FUS)Neas
Genetic
Background		 B6J.129P2(129S)-Mapttm1.1(FUS)Neas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapttm1.1(FUS)Neas mutation (0 available); any Mapt mutation (430 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:232167 )
N
• no denervation of the tibialis anterior neuromuscular junctions is seen at P90




Genotype
MGI:5823842
ht2
Allelic
Composition		 Mapttm1.1(FUS)Neas/Mapt+
Genetic
Background		 B6J.129P2(129S)-Mapttm1.1(FUS)Neas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapttm1.1(FUS)Neas mutation (0 available); any Mapt mutation (430 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:232167 )
N
• mice do not exhibit loss of lumbar level 5 motor neurons or denervation of the tibialis anterior, gastrocnemius, or soleus muscles




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory