Analysis Tools
nervous system
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• motor neuron loss is seen at P60 but not P30, when 10% of lumbar level 5 (L5) motor neurons are lost and by P360, there are 18.6% fewer motor neurons overall in the L5 segment
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• about 10% denervation of the tibialis anterior neuromuscular junctions (NMJs), first seen at P60 which progresses with age such that at P360, about 25% of NMJs are denervated
• denervation is first noted at P120 in the gastrocnemius muscle where about 10% of NMJs are denervated
• however, even at P360, no denervation is seen in the soleus muscle NMJs
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