Analysis Tools
nervous system
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• significant motor neuron loss is seen at P30 but not P10, and by P360, there are 22.6% fewer motor neurons overall in the lumbar level 5 (L5) segment
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• about 10% denervation of the tibialis anterior neuromuscular junctions, first seen at P20 which progresses with age such that at P360, about 30% of NMJs are denervated
• denervation is first noted at P120 in the gastrocnemius muscle where about 13% of NMJs are denervated
• however, even at P360, no denervation is seen in the soleus muscle NMJs
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