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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gpr68tm1Dgen
targeted mutation 1, Deltagen
MGI:5776516
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gpr68tm1Dgen/Gpr68tm1Dgen B6.129P2-Gpr68tm1Dgen MGI:5776530


Genotype
MGI:5776530
hm1
Allelic
Composition		 Gpr68tm1Dgen/Gpr68tm1Dgen
Genetic
Background		 B6.129P2-Gpr68tm1Dgen
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpr68tm1Dgen mutation (0 available); any Gpr68 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
renal/urinary system phenotype ( J:232321 )
N
• mice exhibit normal kdiney morphology
abnormal kidney physiology ( J:232321 )
• at pH 7.1, mice exhibit increased sodium/hydrogen exchanger (NHE) activity in late proximal tubules unlike wild-type mice

respiratory system
respiratory system phenotype ( J:224758 )
N
• mice exhibit normal ventilatory effect of 5% CO2




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory