reproductive system
• both male and female homozygotes are poor breeders
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growth/size/body
• homozygotes are distinctly smaller than unaffected littermates by approximately 5 days of age
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behavior/neurological
• when raised by the tail, homozygotes fail to splay their hind legs outward as if due to a weakness in the hind legs
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• Background Sensitivity: whole body tremor that presents at wean age and persists throughout life is more evident when C57BL/6J is in the genetic background than when BALB/cByJ predominates
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