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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
C1ql3tm1.1Sud
targeted mutation 1.1, Thomas C Sudhof
MGI:5779427
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
C1ql3tm1.1Sud/C1ql3tm1.1Sud involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL MGI:5779515


Genotype
MGI:5779515
cn1
Allelic
Composition
C1ql3tm1.1Sud/C1ql3tm1.1Sud
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
C1ql3tm1.1Sud mutation (1 available); any C1ql3 mutation (18 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice injected with a cre-expressing adenovirus in the posterior insula with infection in anterior the BLA (basolateral amygdala) and PRh (perirhinal) exhibit normal conditioned place preference and other assayed behaviors in an open field test, rotating rod assay and elevated plus maze
• mice injected with a cre-expressing adenovirus in the perirhinal cortices exhibit no phenotype
• mice injected with a cre-expressing adenovirus in the posterior insula with infection in anterior the BLA and PRh exhibit impaired contextual fear memories unlike control mice
• mice injected with a cre-expressing adenovirus in anterior the BLA exhibit impaired cued fear memories unlike control mice





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory