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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Pik3c2gtm1Ehi
targeted mutation 1, Emilio Hirsch
MGI:5779504
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Pik3c2gtm1Ehi/Pik3c2gtm1Ehi involves: 129 * C57BL/6 MGI:5779508


Genotype
MGI:5779508
hm1
Allelic
Composition
Pik3c2gtm1Ehi/Pik3c2gtm1Ehi
Genetic
Background
involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pik3c2gtm1Ehi mutation (0 available); any Pik3c2g mutation (77 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• at 8, but not 2, months under fasted and fed conditions
• when fed a standard chow or a high-fat diet
• - and two-fold increases in serum insulin under fasted and fed conditions, respectively, at 8 months
• when fed a standard chow or a high-fat diet
• when fed a high-fat diet but not when fed standard chow
• when fed a standard chow or a high-fat diet
• at 8, but not 2, months
• mild in mice fed a high-fat diet

liver/biliary system
N
• mice exhibit normal microscopic architecture of the liver parenchyma
• when fed a high-fat diet but not when fed standard chow

growth/size/body
• when fed a high-fat diet

adipose tissue
• in epididymal fat pads
• when fed a standard chow or a high-fat diet

behavior/neurological
N
• mice exhibit normal food intake and physical activity





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory