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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rab7tm1.2Ale
targeted mutation 1.2, Aimee Edinger
MGI:5779674
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rab7tm1.2Ale/Rab7tm1.2Ale involves: 129S1/Sv * 129X1/SvJ MGI:5779675
ht2
 		Rab7tm1.2Ale/Rab7+ involves: 129S1/Sv * 129X1/SvJ MGI:5780295


Genotype
MGI:5779675
hm1
Allelic
Composition		 Rab7tm1.2Ale/Rab7tm1.2Ale
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rab7tm1.2Ale mutation (0 available); any Rab7 mutation (121 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality ( J:211733 )
• no homozygous pups are generated from a heterozygote x heterozygote cross




Genotype
MGI:5780295
ht2
Allelic
Composition		 Rab7tm1.2Ale/Rab7+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rab7tm1.2Ale mutation (0 available); any Rab7 mutation (121 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality, incomplete penetrance ( J:211733 )
• heterozygote x heterozygote matings produce fewer heterozygote mice than expected




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory