All Phenotypes Lepr<m1Clo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lepr^m1Clo
mutation 1, Cecilia Lo
MGI:5780195

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lepr^m1Clo/Lepr^m1Clo	STOCK Lepr^m1Clo/GrsrJ	MGI:5780199

Allelic Composition	Lepr^m1Clo/Lepr^m1Clo
Genetic Background	STOCK Lepr^m1Clo/GrsrJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lepr^m1Clo mutation (1 available); any Lepr mutation (123 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

female infertility ( J:232775 )

reduced male fertility ( J:232775 )

endocrine/exocrine glands

pancreatic islet hyperplasia ( J:232775 )

growth/size/body

obese ( J:232775 )

• homozygotes are fat compared with littermates by 4 weeks of age and become obese with steatosis and islet hyperplasia

liver/biliary system

hepatic steatosis ( J:232775 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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