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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Exd1tm1Embrp
targeted mutation 1, Ramesh Pillai
MGI:5781095
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Exd1tm1Embrp/Exd1tm1Embrp involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JRj MGI:5897684


Genotype
MGI:5897684
hm1
Allelic
Composition		 Exd1tm1Embrp/Exd1tm1Embrp
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JRj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Exd1tm1Embrp mutation (1 available); any Exd1 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:229314 )
N
• mice exhibit normal fertility and viability

reproductive system
abnormal male germ cell physiology ( J:229314 )
• male germline cells exhibit defective biogenesis of antisense piRNAs, activation of transposons and impaired biogenesis of MIWI2 piRNAs
• however, mice exhibit normal fertility

cellular
abnormal male germ cell physiology ( J:229314 )
• male germline cells exhibit defective biogenesis of antisense piRNAs, activation of transposons and impaired biogenesis of MIWI2 piRNAs
• however, mice exhibit normal fertility




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory