taste/olfaction
• the inclusion of a constitutively active GNAS rescues only a few DRY motif-deficient olfactory sensory neurons from loss as assessed at 21 days of age
• although expression of consitutively active GNAS restores the axonal projections to the bulb in these DRY mutant motif receptors, there are fewer than normal olfactory sensory neurons surviving that express this allele, and glomerular formation is therefore inefficient
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craniofacial
• the inclusion of a constitutively active GNAS rescues only a few DRY motif-deficient olfactory sensory neurons from loss as assessed at 21 days of age
• although expression of consitutively active GNAS restores the axonal projections to the bulb in these DRY mutant motif receptors, there are fewer than normal olfactory sensory neurons surviving that express this allele, and glomerular formation is therefore inefficient
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nervous system
• the inclusion of a constitutively active GNAS rescues only a few DRY motif-deficient olfactory sensory neurons from loss as assessed at 21 days of age
• although expression of consitutively active GNAS restores the axonal projections to the bulb in these DRY mutant motif receptors, there are fewer than normal olfactory sensory neurons surviving that express this allele, and glomerular formation is therefore inefficient
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growth/size/body
• the inclusion of a constitutively active GNAS rescues only a few DRY motif-deficient olfactory sensory neurons from loss as assessed at 21 days of age
• although expression of consitutively active GNAS restores the axonal projections to the bulb in these DRY mutant motif receptors, there are fewer than normal olfactory sensory neurons surviving that express this allele, and glomerular formation is therefore inefficient
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respiratory system
• the inclusion of a constitutively active GNAS rescues only a few DRY motif-deficient olfactory sensory neurons from loss as assessed at 21 days of age
• although expression of consitutively active GNAS restores the axonal projections to the bulb in these DRY mutant motif receptors, there are fewer than normal olfactory sensory neurons surviving that express this allele, and glomerular formation is therefore inefficient
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