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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Emg1tm1.1Btr
targeted mutation 1.1, Barbara Triggs-Raine
MGI:5787927
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Emg1tm1.1Btr/Emg1tm1.1Btr involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 MGI:5787933


Genotype
MGI:5787933
hm1
Allelic
Composition
Emg1tm1.1Btr/Emg1tm1.1Btr
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emg1tm1.1Btr mutation (0 available); any Emg1 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

embryo
• open cranial neural tubes in half of mice at E10.5 to E12.5
• in some embryos
• however, the spinal neural tube closes by E12.5
• in one of two mice recovered at E12.5
• less extensive at E11.5 and E12.5 with fewer fetal red blood cells
• however, placenta is normal at E9.5

nervous system
• open cranial neural tubes in half of mice at E10.5 to E12.5
• in some embryos
• however, the spinal neural tube closes by E12.5
• in one of two mice recovered at E12.5
• collapsed telencephalic vesicle in one of two mice recovered at E12.5
• in one of two mice recovered at E12.5

cellular
• in E7.5 to E9.5 embryos
• in E7.5 to E9.5 embryos

growth/size/body

hematopoietic system
• fewer fetal red blood cells at E11.5 and E12.5

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Bowen-Conradi syndrome DOID:0050684 OMIM:211180
J:230556





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory