All Phenotypes Naip5<m1Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Naip5^m1Btlr
mutation 1, Bruce Beutler
MGI:5789561

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Naip5^m1Btlr/Naip5^m1Btlr	C57BL/6J-Naip5^m1Btlr	MGI:5789642

Allelic Composition	Naip5^m1Btlr/Naip5^m1Btlr
Genetic Background	C57BL/6J-Naip5^m1Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Naip5^m1Btlr mutation (0 available); any Naip5 mutation (103 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased interleukin-1 beta secretion ( J:234250 )

• mice exhibited impaired peritoneal macrophage inflammatory responses (i.e., decreased secretion of the proinflammatory cytokine interleukin (IL)-1) in response to priming with flagellin

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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