Analysis Tools
mortality/aging
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• Background Sensitivity: the majority of mice on a C57BL/6J congenic background die within 1 day of birth when this allele is inherited paternally unlike mice on a mixed 129 and C57BL/6J background
• however, mice that survive more than 2 days survive into adulthood
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embryo
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• expanded volume and increased labyrinthine trophoblasts when this allele is inherited maternally
• reduced volume and decreased labyrinthine trophoblasts when this allele is inherited paternally
• however, mice exhibit normal junctional zone, decidual basalis and chorion regardless of allele inheritance
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• increased when this allele is inherited maternally
• decreased when this allele is inherited paternally
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• when this allele is inherited paternally
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• when this allele is inherited maternally, mice exhibit enlarged placenta first apparent at E16.5 and at E18.5 compared with wild-type mice
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• increased theoretical diffusion capacity and specific diffusion capacity when this allele is inherited maternally
• decreased theoretical diffusion capacity and specific diffusion capacity when this allele is inherited paternally
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growth/size/body
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• when this allele is inherited paternally
• however, mice exhibit normal fetal weight and after birth growth when this allele is inherited maternally
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• into adulthood when this allele is inherited paternally
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• at E16.5 when this allele is inherited paternally
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