All Phenotypes Ptchd1<tm2.1Gfng> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ptchd1^tm2.1Gfng
targeted mutation 2.1, Guoping Feng
MGI:5792576

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ptchd1^tm2.1Gfng/Y Sst^{tm2.1(cre)Zjh}/Sst⁺	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J	MGI:5792694

Allelic Composition	Ptchd1^tm2.1Gfng/Y Sst^{tm2.1(cre)Zjh}/Sst⁺
Genetic Background	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptchd1^tm2.1Gfng mutation (1 available); any Ptchd1 mutation (11 available)
Sst^{tm2.1(cre)Zjh} mutation (4 available); any Sst mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:232709 )

N	• mice exhibit normal hypertonia and no hyper-aggression

abnormal cognition ( J:232709 )

• attention deficits as in knock-out mice

hyperactivity ( J:232709 )

fragmentation of sleep/wake states ( J:232709 )

• highly fragmented sleep

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