limbs/digits/tail
• the hind legs are malformed and may be twisted, misshapen, and misplaced on the body
|
• all four feet have abnormal digits, which can include polydactyly, syndactyly and shortened toes
|
polydactyly
(
J:235124
)
syndactyly
(
J:235124
)
mortality/aging
• only 36 mutants were identified in 96 offspring (38.1%) of heterozygous females bred to C57BL/6J males, less than predicted by Mendlian inheritance
|