Allele Symbol Allele Name Allele ID |
Ctnnbl1tm1.1Crad targeted mutation 1.1, Cristina Rada MGI:5795658 |
||||||||||||||||
Summary |
3 genotypes
|
|
|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
|
|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
N |
• mice exhibit normal splenic B cells numbers and early stages of B cell differentiation
|
• delayed entry into S phase on activation of resting, affecting follicular more than marginal zone B cells
|
• in response to LPS or anti-CD40 stimulation
|
• reduced immunoglobin class switching in splenic B cells
|
• delayed entry into S phase on activation of resting, affecting follicular more than marginal zone B cells
|
• in response to LPS or anti-CD40 stimulation
|
• reduced immunoglobin class switching in splenic B cells
|
• delayed entry into S phase on activation of resting, affecting follicular more than marginal zone B cells
|
• in response to LPS or anti-CD40 stimulation
|
|
|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• in response to LPS or anti-CD40 stimulation
|
• in response to LPS or anti-CD40 stimulation
|
• in response to LPS or anti-CD40 stimulation
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 12/10/2024 MGI 6.24 |
|
|