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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Traf3ip3tm1c(KOMP)Wtsi
targeted mutation 1c, Wellcome Trust Sanger Institute
MGI:5795738
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Gt(ROSA)26Sortm8(Map2k1*,EGFP)Rsky/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0
Traf3ip3tm1c(KOMP)Wtsi/Traf3ip3tm1c(KOMP)Wtsi
involves: C57BL/6 * C57BL/6N * DBA/2 MGI:5795855


Genotype
MGI:5795855
cn1
Allelic
Composition
Gt(ROSA)26Sortm8(Map2k1*,EGFP)Rsky/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0
Traf3ip3tm1c(KOMP)Wtsi/Traf3ip3tm1c(KOMP)Wtsi
Genetic
Background
involves: C57BL/6 * C57BL/6N * DBA/2
Cell Lines EPD0093_2_B04
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm8(Map2k1*,EGFP)Rsky mutation (1 available); any Gt(ROSA)26Sor mutation (993 available)
Tg(Cd4-cre)1Cwi mutation (10 available)
Traf3ip3tm1c(KOMP)Wtsi mutation (0 available); any Traf3ip3 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• constitutively active Map2k1(MEK) rescues thymocyte development restoring single positive thymocyte and splenic T cell populations





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory