Phenotypes associated with this allele

• Allele Symbol: Nalcn^Drl
• Allele Name: dreamless
• Allele ID: MGI:5800457
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Nalcn^Drl/Nalcn^+	involves: C57BL/6J * C57BL/6N	MGI:5806615

Genotype
MGI:5806615

ht1

• Allelic Composition: Nalcn^Drl/Nalcn⁺
• Genetic Background: involves: C57BL/6J * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:236598 )

N • total time spent in wake and non-rapid eye movement sleep (NREMS) is normal

abnormal circadian behavior ( J:236598 )

• under constant darkness, mice exhibit reduced amplitude of behavioral circadian rhythm compared with wild-type mice

• however, mice exhibit normal circadian period lengths

abnormal paradoxical sleep pattern ( J:236598 )

• short rapid eye movement sleep (REMS) episode duration and total REMS time resulting in highly unstable REMS compared with wild-type mice

• under constant darkness, mice exhibit reduced REMS time compared with wild-type mice

nervous system

abnormal nervous system electrophysiology ( J:236598 )

• deep mesencephalic neurons exhibit depolarization and higher spontaneous firing rates compared with wild-type mice

abnormal brain wave pattern ( J:236598 )

• mice exhibit decreased theta-range power during non-rapid eye movement sleep (NREMS) and short rapid eye movement sleep (REMS) and increased low-frequency power during the wake state and EMS compared with wild-type mice