About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dnm1tm2.2Frk
targeted mutation 2.2, Wayne N Frankel
MGI:5800541
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Dnm1tm2.2Frk/Dnm1tm2.2Frk B6.129(Cg)-Dnm1tm2.2Frk MGI:5800568
ht2
Dnm1Ftfl/Dnm1tm2.2Frk involves: 129 * C57BL/6J * FVB MGI:5800569


Genotype
MGI:5800568
hm1
Allelic
Composition
Dnm1tm2.2Frk/Dnm1tm2.2Frk
Genetic
Background
B6.129(Cg)-Dnm1tm2.2Frk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnm1tm2.2Frk mutation (0 available); any Dnm1 mutation (40 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• mice do not display spontaneous seizures and exhibit a normal electroconvulsive threshold




Genotype
MGI:5800569
ht2
Allelic
Composition
Dnm1Ftfl/Dnm1tm2.2Frk
Genetic
Background
involves: 129 * C57BL/6J * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnm1Ftfl mutation (2 available); any Dnm1 mutation (40 available)
Dnm1tm2.2Frk mutation (0 available); any Dnm1 mutation (40 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• non-maximal, non-lethal seizures without interictal events similar to Dnm1Ftfl heterozygotes

behavior/neurological
• non-maximal, non-lethal seizures without interictal events similar to Dnm1Ftfl heterozygotes





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/19/2024
MGI 6.24
The Jackson Laboratory