Phenotypes associated with this allele

• Allele Symbol: Cep135^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:5805217
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cep135^em1(IMPC)J/Cep135^em1(IMPC)J	C57BL/6NJ-Cep135^em1(IMPC)J/J	MGI:6262106
ht2	Cep135^em1(IMPC)J/Cep135^+	C57BL/6NJ-Cep135^em1(IMPC)J/J	MGI:6370391

Genotype
MGI:6262106

hm1

• Allelic Composition: Cep135^em1(IMPC)J/Cep135^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Cep135^em1(IMPC)J/J

Data Sources

IMPC Data for Cep135

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

♀

IMPC - JAX

facial cleft ( J:211773 )

♂

IMPC - JAX

abnormal head shape ( J:211773 )

IMPC - JAX

growth/size/body

facial cleft ( J:211773 )

♂

IMPC - JAX

abnormal head shape ( J:211773 )

IMPC - JAX

homeostasis/metabolism

edema ( J:211773 )

IMPC - JAX

limbs/digits/tail

polydactyly ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

vision/eye

microphthalmia ( J:211773 )

♂

IMPC - JAX

anophthalmia ( J:211773 )

IMPC - JAX

Genotype
MGI:6370391

ht2

• Allelic Composition: Cep135^em1(IMPC)J/Cep135⁺
• Genetic Background: C57BL/6NJ-Cep135^em1(IMPC)J/J

Data Sources

IMPC Data for Cep135

growth/size/body

abnormal head morphology ( J:211773 )

IMPC - JAX

homeostasis/metabolism

decreased circulating serum albumin level ( J:211773 )

IMPC - JAX

increased circulating total protein level ( J:211773 )

IMPC - JAX

skeleton

decreased bone mineral density ( J:211773 )

♂

IMPC - JAX

vision/eye

abnormal lens morphology ( J:211773 )

IMPC - JAX

cataract ( J:211773 )

IMPC - JAX