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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Per2M1Btlr
mutation 1, Bruce Beutler
MGI:5805980
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Per2M1Btlr/Per2M1Btlr C57BL/6J-Per2M1Btlr MGI:5906447
ht2
 		Per2M1Btlr/Per2+ C57BL/6J-Per2M1Btlr MGI:5906453


Genotype
MGI:5906447
hm1
Allelic
Composition		 Per2M1Btlr/Per2M1Btlr
Genetic
Background		 C57BL/6J-Per2M1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Per2M1Btlr mutation (1 available); any Per2 mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal circadian behavior ( J:264638 )
• shortened free-running period in constant darkness and an advanced phase of entrainment compared to wild-type controls
shortened circadian behavior period ( J:101977 )
• mice exhibit a short circadian period in constant darkness

nervous system
abnormal brain wave pattern ( J:101977 )
• mice exhibit an advanced phase of neural entrainment; becoming active earlier as compared to heterozygote or wild-type mice

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
advanced sleep phase syndrome 1 DOID:0110011 OMIM:604348
 J:264638




Genotype
MGI:5906453
ht2
Allelic
Composition		 Per2M1Btlr/Per2+
Genetic
Background		 C57BL/6J-Per2M1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Per2M1Btlr mutation (1 available); any Per2 mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
shortened circadian behavior period ( J:101977 )
• mice exhibit a short circadian period in constant darkness




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory