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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Itgamm1Btlr
mutation 1, Bruce Beutler
MGI:5806334
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Itgamm1Btlr/Itgamm1Btlr C57BL/6J-Itgamm1Btlr MGI:5807157
ht2
 		Itgamm1Btlr/Itgam+ C57BL/6J-Itgamm1Btlr MGI:5807158


Genotype
MGI:5807157
hm1
Allelic
Composition		 Itgamm1Btlr/Itgamm1Btlr
Genetic
Background		 C57BL/6J-Itgamm1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgamm1Btlr mutation (0 available); any Itgam mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal dendritic cell number ( J:236681 )
• reduced frequency of CD11b+ dendritic cells (DCs) gated in CD11c+ cells and an increased frequency of CD8a+ DCs gated in CD11c+ cells

immune system
abnormal dendritic cell number ( J:236681 )
• reduced frequency of CD11b+ dendritic cells (DCs) gated in CD11c+ cells and an increased frequency of CD8a+ DCs gated in CD11c+ cells




Genotype
MGI:5807158
ht2
Allelic
Composition		 Itgamm1Btlr/Itgam+
Genetic
Background		 C57BL/6J-Itgamm1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgamm1Btlr mutation (0 available); any Itgam mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal dendritic cell number ( J:236681 )
• reduced frequency of CD11b+ dendritic cells (DCs) gated in CD11c+ cells and an increased frequency of CD8a+ DCs gated in CD11c+ cells

immune system
abnormal dendritic cell number ( J:236681 )
• reduced frequency of CD11b+ dendritic cells (DCs) gated in CD11c+ cells and an increased frequency of CD8a+ DCs gated in CD11c+ cells




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory