About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sppl2am1Btlr
mutation 1, Bruce Beutler
MGI:5806432
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sppl2am1Btlr/Sppl2am1Btlr C57BL/6J-Sppl2am1Btlr MGI:5807184


Genotype
MGI:5807184
hm1
Allelic
Composition		 Sppl2am1Btlr/Sppl2am1Btlr
Genetic
Background		 C57BL/6J-Sppl2am1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sppl2am1Btlr mutation (0 available); any Sppl2a mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased IgG level ( J:236687 )
• mice show reduced T-dependent antibody responses to ovalbumin administered with aluminum hydroxide

immune system
decreased IgG level ( J:236687 )
• mice show reduced T-dependent antibody responses to ovalbumin administered with aluminum hydroxide




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory