All Phenotypes Dock2<m6Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Dock2^m6Btlr
mutation 6, Bruce Beutler
MGI:5806434

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dock2^m6Btlr/Dock2^m6Btlr	C57BL/6J-Dock2^m6Btlr	MGI:5807200

Allelic Composition	Dock2^m6Btlr/Dock2^m6Btlr
Genetic Background	C57BL/6J-Dock2^m6Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock2^m6Btlr mutation (0 available); any Dock2 mutation (143 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased IgE level ( J:236689 )

• in unstimulated mice

• of ovalbumin-specific IgE after immunization with ovalbumin administered with aluminum hydroxide

decreased response to antigen ( J:236689 )

• increased ovalbumin-specific IgE after immunization with ovalbumin administered with aluminum hydroxide

hematopoietic system

decreased IgE level ( J:236689 )

• in unstimulated mice

• of ovalbumin-specific IgE after immunization with ovalbumin administered with aluminum hydroxide

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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