All Phenotypes Pik3r1<em1Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pik3r1^em1Btlr
endonuclease-mediated mutation 1, Bruce Beutler
MGI:5806486

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Kbtbd2^em1Btlr/Kbtbd2^em1Btlr Pik3r1^em1Btlr/Pik3r1^em1Btlr	Not Specified	MGI:5806515

Allelic Composition	Kbtbd2^em1Btlr/Kbtbd2^em1Btlr Pik3r1^em1Btlr/Pik3r1^em1Btlr
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kbtbd2^em1Btlr mutation (0 available); any Kbtbd2 mutation (50 available)
Pik3r1^em1Btlr mutation (0 available); any Pik3r1 mutation (56 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased circulating glucose level ( J:236520 )

• 11 week old male mice exhibit decreased serum glucose levels compared with Kbtbd2^em1Btlr homozygotes

decreased circulating insulin level ( J:236520 )

• 11 week old male mice exhibit decreased serum insulin levels compared with Kbtbd2^em1Btlr homozygotes

increased insulin sensitivity ( J:236520 )

• in 11 week old male compared with Kbtbd2^em1Btlr homozygotes

growth/size/body

increased body fat mass ( J:236520 )

• 11 week old male mice exhibit increased fat weight compared with Kbtbd2^em1Btlr homozygotes

increased body weight ( J:236520 )

• 11 week old male mice exhibit increased body weight compared with Kbtbd2^em1Btlr homozygotes

adipose tissue

increased body fat mass ( J:236520 )

• 11 week old male mice exhibit increased fat weight compared with Kbtbd2^em1Btlr homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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