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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rab43tm1.2Kmm
targeted mutation 1.2, Kenneth Murphy
MGI:5807220
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rab43tm1.2Kmm/Rab43tm1.2Kmm B6.129S(C)-Rab43tm1.2Kmm MGI:5807229


Genotype
MGI:5807229
hm1
Allelic
Composition		 Rab43tm1.2Kmm/Rab43tm1.2Kmm
Genetic
Background		 B6.129S(C)-Rab43tm1.2Kmm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rab43tm1.2Kmm mutation (1 available); any Rab43 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal dendritic cell antigen presentation ( J:101977 )
• defective cross-presentation of cell-associated antigen by classical dendritic cells (CD8alpha+)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/05/2024
MGI 6.24 		The Jackson Laboratory