Phenotypes associated with this allele

• Allele Symbol: Cul4a^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5807494
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cul4a^tm1b(EUCOMM)Hmgu/Cul4a^tm1b(EUCOMM)Hmgu	C57BL/6N-Cul4a^tm1b(EUCOMM)Hmgu/Ccpcz	MGI:6408322

Genotype
MGI:6408322

hm1

• Allelic Composition: Cul4a^{tm1b(EUCOMM)Hmgu}/Cul4a^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Cul4a^{tm1b(EUCOMM)Hmgu}/Ccpcz
• Cell Lines: HEPD0649_1_F11

Data Sources

IMPC Data for Cul4a

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

enhanced cued conditioning behavior ( J:211773 )

♀

IMPC - CCP-IMG

decreased exploration in new environment ( J:211773 )

♂

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

decreased mean platelet volume ( J:211773 )

♂

IMPC - CCP-IMG

decreased spleen weight ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♂

IMPC - CCP-IMG

increased circulating potassium level ( J:211773 )

♂

IMPC - CCP-IMG

decreased circulating chloride level ( J:211773 )

♂

IMPC - CCP-IMG

immune system

decreased spleen weight ( J:211773 )

IMPC - CCP-IMG

reproductive system

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

male infertility ( J:211773 )

♂

IMPC - CCP-IMG

vision/eye

abnormal retina morphology ( J:211773 )

IMPC - CCP-IMG