Phenotypes associated with this allele

• Allele Symbol: Sh3tc1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5812928
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sh3tc1^tm1b(EUCOMM)Hmgu/Sh3tc1^tm1b(EUCOMM)Hmgu	C57BL/6N-Sh3tc1^tm1b(EUCOMM)Hmgu/Orl	MGI:6263465

Genotype
MGI:6263465

hm1

• Allelic Composition: Sh3tc1^{tm1b(EUCOMM)Hmgu}/Sh3tc1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Sh3tc1^{tm1b(EUCOMM)Hmgu}/Orl
• Cell Lines: HEPD0746_3_C10

Data Sources

IMPC Data for Sh3tc1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - ICS

cardiovascular system

decreased cardiac muscle contractility ( J:211773 )

♀

IMPC - ICS

prolonged QT interval ( J:211773 )

♀

IMPC - ICS

prolonged ST segment ( J:211773 )

IMPC - ICS

hematopoietic system

increased neutrophil cell number ( J:211773 )

♂

IMPC - ICS

increased monocyte cell number ( J:211773 )

♂

IMPC - ICS

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♀

IMPC - ICS

decreased circulating triglyceride level ( J:211773 )

♂

IMPC - ICS

immune system

increased neutrophil cell number ( J:211773 )

♂

IMPC - ICS

increased monocyte cell number ( J:211773 )

♂

IMPC - ICS

muscle

decreased cardiac muscle contractility ( J:211773 )

♀

IMPC - ICS

vision/eye

abnormal vitreous body morphology ( J:211773 )

♀

IMPC - ICS