All Phenotypes Got1<tm1b(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Got1^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5812935

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Got1^{tm1b(EUCOMM)Hmgu}/Got1^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Got1^{tm1b(EUCOMM)Hmgu}/H	MGI:6262549
ht2	Got1^{tm1b(EUCOMM)Hmgu}/Got1⁺	C57BL/6N-Got1^{tm1b(EUCOMM)Hmgu}/H	MGI:6262548

Allelic Composition	Got1^{tm1b(EUCOMM)Hmgu}/Got1^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Got1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0721_3_C02

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Got1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Got1 mutation (47 available)

Data Sources

IMPC Data for Got1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Got1^{tm1b(EUCOMM)Hmgu}/Got1⁺
Genetic Background	C57BL/6N-Got1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0721_3_C02

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Got1^{tm1b(EUCOMM)Hmgu} mutation (1 available); any Got1 mutation (47 available)

Data Sources

IMPC Data for Got1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

prolonged RR interval ( J:211773 )

IMPC - HAR

hematopoietic system

decreased leukocyte cell number ( J:211773 )

IMPC - HAR

decreased basophil cell number ( J:211773 )

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

IMPC - HAR

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

IMPC - HAR

immune system

decreased leukocyte cell number ( J:211773 )

IMPC - HAR

decreased basophil cell number ( J:211773 )

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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