Phenotypes associated with this allele

• Allele Symbol: Txlna^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5817709
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Txlna^tm1b(EUCOMM)Hmgu/Txlna^tm1b(EUCOMM)Hmgu	C57BL/6N-Txlna^tm1b(EUCOMM)Hmgu/H	MGI:6263802
ht2	Txlna^tm1b(EUCOMM)Hmgu/Txlna^+	C57BL/6N-Txlna^tm1b(EUCOMM)Hmgu/H	MGI:6263801

Genotype
MGI:6263802

hm1

• Allelic Composition: Txlna^{tm1b(EUCOMM)Hmgu}/Txlna^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Txlna^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0641_5_B10

Data Sources

IMPC Data for Txlna

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - HAR

endocrine/exocrine glands

small testis ( J:211773 )

♂

IMPC - HAR

hematopoietic system

increased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

increased large unstained cell number ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

increased circulating potassium level ( J:211773 )

♂

IMPC - HAR

immune system

increased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

increased large unstained cell number ( J:211773 )

♀

IMPC - HAR

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

reproductive system

small testis ( J:211773 )

♂

IMPC - HAR

Genotype
MGI:6263801

ht2

• Allelic Composition: Txlna^{tm1b(EUCOMM)Hmgu}/Txlna⁺
• Genetic Background: C57BL/6N-Txlna^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0641_5_B10

Data Sources

IMPC Data for Txlna

behavior/neurological

abnormal gait ( J:211773 )

♂

IMPC - HAR

hematopoietic system

decreased hemoglobin content ( J:211773 )

♀

IMPC - HAR

increased large unstained cell number ( J:211773 )

♂

IMPC - HAR

immune system

increased large unstained cell number ( J:211773 )

♂

IMPC - HAR