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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd83tm1.1Lnjt
targeted mutation 1.1, Lars Nitschke
MGI:5819103
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cd83tm1.1Lnjt/Cd83tm1.1Lnjt involves: C57BL/6 * C57BL/6N MGI:5903298
cx2
 		Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
Marchf8tm1.1Lkle/Marchf8tm1.1Lkle 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N MGI:5903297
cx3
 		Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
Marchf1tm1.1Sish/Marchf1tm1.1Sish 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N MGI:5903300
cx4
 		Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
H2-Ab1b-tm2Hpl/H2-Ab1b-tm2Hpl 		involves: 129S4/SvJae * C57BL/6 * C57BL/6N MGI:5903299


Genotype
MGI:5903298
hm1
Allelic
Composition		 Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
Genetic
Background		 involves: C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd83tm1.1Lnjt mutation (0 available); any Cd83 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system

immune system




Genotype
MGI:5903297
cx2
Allelic
Composition		 Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
Marchf8tm1.1Lkle/Marchf8tm1.1Lkle
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd83tm1.1Lnjt mutation (0 available); any Cd83 mutation (17 available)
Marchf8tm1.1Lkle mutation (0 available); any Marchf8 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:236611 )
N
• normal CD4+ T cell compartment in the thymus unlike in Cd83tm1.1Lnjt homozygotes




Genotype
MGI:5903300
cx3
Allelic
Composition		 Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
Marchf1tm1.1Sish/Marchf1tm1.1Sish
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd83tm1.1Lnjt mutation (0 available); any Cd83 mutation (17 available)
Marchf1tm1.1Sish mutation (1 available); any Marchf1 mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased CD4-positive, alpha-beta T cell number ( J:236611 )
• in the thymus as in Cd83tm1.1Lnjt homozygotes

hematopoietic system
decreased CD4-positive, alpha-beta T cell number ( J:236611 )
• in the thymus as in Cd83tm1.1Lnjt homozygotes




Genotype
MGI:5903299
cx4
Allelic
Composition		 Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
H2-Ab1b-tm2Hpl/H2-Ab1b-tm2Hpl
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd83tm1.1Lnjt mutation (0 available); any Cd83 mutation (17 available)
H2-Ab1b-tm2Hpl mutation (0 available); any H2-Ab1 mutation (83 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:236611 )
N
• normal CD4+ T cell compartment in the thymus unlike in Cd83tm1.1Lnjt homozygotes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory