Phenotypes associated with this allele

• Allele Symbol: Ube3d^em1Xxl
• Allele Name: endonuclease-mediated mutation 1, Xiao-Xin Li
• Allele ID: MGI:5825270
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ube3d^em1Xxl/Ube3d^em1Xxl	Not Specified	MGI:5825271
ht2	Ube3d^em1Xxl/Ube3d^+	Not Specified	MGI:5825272

Genotype
MGI:5825271

hm1

• Allelic Composition: Ube3d^em1Xxl/Ube3d^em1Xxl
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:233507 )

• no mice are obtained while heterozygotes survive

Genotype
MGI:5825272

ht2

• Allelic Composition: Ube3d^em1Xxl/Ube3d⁺
• Genetic Background: Not Specified

vision/eye

abnormal retina pigment epithelium morphology ( J:233507 )

• at 3 months, mice exhibit more loose retinal pigment epithelium microvilli and more pigment granules compared with wild-type mice

abnormal eye electrophysiology ( J:233507 )

• decreased a- and b-wave amplitude

pigmentation

abnormal retina pigment epithelium morphology ( J:233507 )

• at 3 months, mice exhibit more loose retinal pigment epithelium microvilli and more pigment granules compared with wild-type mice