Phenotypes associated with this allele

• Allele Symbol: Pik3r6^tm1.1Lste
• Allele Name: targeted mutation 1.1, Len Stephens
• Allele ID: MGI:5829800
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pik3r6^tm1.1Lste/Pik3r6^tm1.1Lste	Not Specified	MGI:5903754

Genotype
MGI:5903754

hm1

• Allelic Composition: Pik3r6^tm1.1Lste/Pik3r6^tm1.1Lste
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:238900 )

N • neutrophils exhibit normal accumulation in the peritoneum in response to thioglycollate and normal chemokinetic responses

increased neutrophil cell number ( J:238900 )

• slightly

decreased granulocyte number ( J:238900 )

• small reduction

decreased lymphocyte cell number ( J:238900 )

• small reduction

abnormal neutrophil physiology ( J:238900 )

• reduced reactive oxygen species formation in response to GPCR stimulation

• however, neutrophils exhibit normal migration response to GPCR stimulation

hematopoietic system

increased neutrophil cell number ( J:238900 )

• slightly

decreased granulocyte number ( J:238900 )

• small reduction

decreased lymphocyte cell number ( J:238900 )

• small reduction

abnormal neutrophil physiology ( J:238900 )

• reduced reactive oxygen species formation in response to GPCR stimulation

• however, neutrophils exhibit normal migration response to GPCR stimulation