All Phenotypes Slc13a4<tm1d(EUCOMM)Wtsi> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Slc13a4^{tm1d(EUCOMM)Wtsi}
targeted mutation 1d, Wellcome Trust Sanger Institute
MGI:5881938

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc13a4^{tm1d(EUCOMM)Wtsi}/Slc13a4^{tm1d(EUCOMM)Wtsi}	involves: C57BL/6 * CBA	MGI:5896627
cn2	Slc13a4^{tm1c(EUCOMM)Wtsi}/Slc13a4^{tm1d(EUCOMM)Wtsi} Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺	involves: C57BL/6 * CBA	MGI:5896626

Allelic Composition	Slc13a4^{tm1d(EUCOMM)Wtsi}/Slc13a4^{tm1d(EUCOMM)Wtsi}
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc13a4^{tm1d(EUCOMM)Wtsi} mutation (0 available); any Slc13a4 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:239786 )

• all are dead by E18.5, phenocoping mice homozygous for Slc13a4 ^{tm1a(EUCOMM)Wtsi}

Allelic Composition	Slc13a4^{tm1c(EUCOMM)Wtsi}/Slc13a4^{tm1d(EUCOMM)Wtsi} Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edil3^{Tg(Sox2-cre)1Amc} mutation (5 available); any Edil3 mutation (43 available)
Slc13a4^{tm1c(EUCOMM)Wtsi} mutation (0 available); any Slc13a4 mutation (34 available)
Slc13a4^{tm1d(EUCOMM)Wtsi} mutation (0 available); any Slc13a4 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:239786 )

N	• with paternal inheritance of the cre transgene mice are viable

lethality throughout fetal growth and development, complete penetrance ( J:239786 )

• with maternal inheritance of the cre transgene these mice phenocopy mice homozygous for Slc13a4 ^{tm1a(EUCOMM)Wtsi}

embryo

embryo phenotype ( J:239786 )

N	• with paternal inheritance of the cre transgene restricting cre expression to the embryo and not the extraembryonic tissues, placental transport of sulfate is similar to controls and embryos resemble controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24