All Phenotypes Repin1<tm1.2Arte> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Repin1^tm1.2Arte
targeted mutation 1.2, TaconicArtemis
MGI:5882542

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Lepr^db/Lepr^db Repin1^tm1.2Arte/Repin1^tm1.2Arte	involves: BALB/c * C57BL/6 * C57BLKS/J	MGI:5903475

Allelic Composition	Lepr^db/Lepr^db Repin1^tm1.2Arte/Repin1^tm1.2Arte
Genetic Background	involves: BALB/c * C57BL/6 * C57BLKS/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lepr^db mutation (17 available); any Lepr mutation (122 available)
Repin1^tm1.2Arte mutation (0 available); any Repin1 mutation (48 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body fat mass ( J:238672 )

• at 20 weeks compared with Lepr^db homozygotes

decreased body weight ( J:238672 )

• at 8 to 20 weeks compared with Lepr^db homozygotes

• however, body length is normal

adipose tissue

decreased body fat mass ( J:238672 )

• at 20 weeks compared with Lepr^db homozygotes

abnormal adipose tissue physiology ( J:238672 )

• reduced inflammatory infiltrate compared with Lepr^db homozygotes

homeostasis/metabolism

decreased circulating glucose level ( J:238672 )

• compared with Lepr^db homozygotes

increased insulin sensitivity ( J:238672 )

• compared with Lepr^db homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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