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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Stub1em1Schiz
endonuclease-mediated mutation 1, Jonathan Schisler
MGI:5883530
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Stub1em1Schiz/Stub1em1Schiz C57BL/6J-Stub1em1Schiz MGI:6154591


Genotype
MGI:6154591
hm1
Allelic
Composition
Stub1em1Schiz/Stub1em1Schiz
Genetic
Background
C57BL/6J-Stub1em1Schiz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stub1em1Schiz mutation (0 available); any Stub1 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• cumulative fluid intake is lower than in controls

homeostasis/metabolism
• increase in urine chloride level
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• increase in urine potassium concentration
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• increase in urine sodium level
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• urine osmolality is higher than in controls
• however, baseline serum electrolytes are normal
• increase in urine baseline urea level
• however, when normalized to creatinine, no differences are seen

renal/urinary system
• increase in urine chloride level
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• increase in urine potassium concentration
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• increase in urine sodium level
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• urine osmolality is higher than in controls
• however, baseline serum electrolytes are normal
• increase in urine baseline urea level
• however, when normalized to creatinine, no differences are seen





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory