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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dusp5tm1d(KOMP)Wtsi
targeted mutation 1d, Wellcome Trust Sanger Institute
MGI:5888995
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dusp5tm1d(KOMP)Wtsi/Dusp5tm1d(KOMP)Wtsi B6(Cg)-Dusp5tm1d(KOMP)Wtsi MGI:5906376


Genotype
MGI:5906376
hm1
Allelic
Composition		 Dusp5tm1d(KOMP)Wtsi/Dusp5tm1d(KOMP)Wtsi
Genetic
Background		 B6(Cg)-Dusp5tm1d(KOMP)Wtsi
Cell Lines EPD0575_3_B05
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dusp5tm1d(KOMP)Wtsi mutation (0 available); any Dusp5 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased T cell apoptosis ( J:240637 )
• cultured short-lived effector and memory precursor effector T cells exhibit increased necrotic cells with reduced live cells compared with wild-type mice

cellular
increased T cell apoptosis ( J:240637 )
• cultured short-lived effector and memory precursor effector T cells exhibit increased necrotic cells with reduced live cells compared with wild-type mice

hematopoietic system
increased T cell apoptosis ( J:240637 )
• cultured short-lived effector and memory precursor effector T cells exhibit increased necrotic cells with reduced live cells compared with wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory