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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Otp-cre)1Hzo
transgene insertion 1, Huda Y Zoghbi
MGI:5897831
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi
Tg(Otp-cre)1Hzo/0
involves: C57BL/6 * C57BL/6N * FVB/N MGI:6275616


Genotype
MGI:6275616
cn1
Allelic
Composition
Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi
Tg(Otp-cre)1Hzo/0
Genetic
Background
involves: C57BL/6 * C57BL/6N * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cictm1c(KOMP)Wtsi mutation (1 available); any Cic mutation (98 available)
Tg(Otp-cre)1Hzo mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• in the resident-intruder test, mice behave more aggressively toward intruders, with more frequent and longer attack episodes
• in the three-chamber test, mice interact less with other mice
• however, mice do not exhibit abnormal behavior in the open-field, elevated plus-maze, or fear conditioning assay
• in the partition test, mice spend less time interacting with novel mice

nervous system
N
• no gross abnormalities or altered cellularity of Otp-lineage neurons are seen





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory