digestive/alimentary system
• decrease in the overall thickness of the antral mucosa compared to mice homozygous for the Il6st mutation not carrying the transgene
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• decrease in antral tumor growth compared to mice homozygous for the Il6st mutation not carrying the transgene suggesting overexpression of GNK2 as a possible therapy for gastric cancer
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hematopoietic system
• decrease in the splenomegaly phenotype typically seen in mice homozygous for the Il6st mutation not carrying the transgene
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neoplasm
• decrease in antral tumor growth compared to mice homozygous for the Il6st mutation not carrying the transgene suggesting overexpression of GNK2 as a possible therapy for gastric cancer
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immune system
• decrease in the splenomegaly phenotype typically seen in mice homozygous for the Il6st mutation not carrying the transgene
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