All Phenotypes Mahl<129S1/SvImJ> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mahl^129S1/SvImJ
129S1/SvImJ
MGI:5898321

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Cdh23^ahl/Cdh23^tm1.1Kjn Mahl^C57BL/6J/Mahl^129S1/SvImJ	(129S1.B6-(rs3696307-rs257098870)/Kjn x 129S/Sv-Cdh23^tm1.1Kjn/Kjn)F1	MGI:5898375

Allelic Composition	Cdh23^ahl/Cdh23^tm1.1Kjn Mahl^C57BL/6J/Mahl^129S1/SvImJ
Genetic Background	(129S1.B6-(rs3696307-rs257098870)/Kjn x 129S/Sv-Cdh23^tm1.1Kjn/Kjn)F1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdh23^ahl mutation (55 available); any Cdh23 mutation (281 available)
Cdh23^tm1.1Kjn mutation (1 available); any Cdh23 mutation (281 available)
Mahl^129S1/SvImJ mutation (1 available); any Mahl mutation (2 available)
Mahl^C57BL/6J mutation (1 available); any Mahl mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hearing/vestibular/ear

increased or absent threshold for auditory brainstem response ( J:241137 )

• these mice, homozygous for the c.735A point mutation that causes age related hearing loss and heterozgyous for the ameliorating C57BL/6J-derived modifier, have a 16 kHz ABR threshold at 3 months of age that is less than mice homozygous for the 129S1/SvImJ-derived modifier, proving the C57BL/6J allele dominant

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